Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | CHAT | P28329 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573242 | 1.00 | MEN1 (0.37) | MEN1KMT2AMAPTHTTMITF | |
| SCHEMBL7573259 | 0.89 | MAPT (0.43) | MEN1KMT2AMAPTHTTMITF | |
| SCHEMBL7573263 | 0.89 | MAPT (0.43) | MEN1KMT2AMAPTHTTMITF | |
| SCHEMBL7571835 | 0.87 | CHRM5 (0.43) | MEN1KMT2AMAPTHTTMITF | |
| SCHEMBL7571831 | 0.87 | CHRM5 (0.43) | MEN1KMT2AMAPTHTTMITF | |
| SCHEMBL7580519 | 0.82 | MAPT (0.39) | MEN1KMT2AMAPTHTTMITF | |
| SCHEMBL7580528 | 0.82 | MAPT (0.39) | MEN1KMT2AMAPTHTTMITF | |
| SCHEMBL7580532 | 0.81 | MAPT (0.47) | MEN1KMT2AMAPTHTTNPC1 | |
| SCHEMBL7571819 | 0.81 | CYP1A2 (0.39) | MEN1KMT2AMAPTHTTMITF | |
| SCHEMBL7571823 | 0.81 | CYP1A2 (0.39) | MEN1KMT2AMAPTHTTMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810199-B1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5756769-A | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0810199-A1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |