Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | RRM1 | P23921 | 2/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.38 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.38 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573389 | 0.88 | MEN1 (0.49) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7573263 | 0.83 | MAPT (0.43) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7573259 | 0.83 | MAPT (0.43) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7571301 | 0.83 | CTDSP1 (0.40) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7571297 | 0.83 | CTDSP1 (0.40) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7573246 | 0.81 | MEN1 (0.37) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7573242 | 0.81 | MEN1 (0.37) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7579065 | 0.80 | MEN1 (0.49) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7579070 | 0.80 | MEN1 (0.49) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7575183 | 0.79 | IKBKB (0.48) | MAPTMEN1KMT2AALDH1A1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810199-B1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5756769-A | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0810199-A1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |