Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CHAT | P28329 | 2/20 | 0.40 |
| ▸ | RRM1 | P23921 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573263 | 1.00 | MAPT (0.43) | MAPTMEN1KMT2AHTTMITF | |
| SCHEMBL7573246 | 0.89 | MEN1 (0.37) | MAPTMEN1KMT2AHTTMITF | |
| SCHEMBL7573242 | 0.89 | MEN1 (0.37) | MAPTMEN1KMT2AHTTMITF | |
| SCHEMBL7571831 | 0.86 | CHRM5 (0.43) | MAPTMEN1KMT2AHTTMITF | |
| SCHEMBL7571835 | 0.86 | CHRM5 (0.43) | MAPTMEN1KMT2AHTTMITF | |
| SCHEMBL7580532 | 0.83 | MAPT (0.47) | MAPTMEN1KMT2AHTTKDM4E | |
| SCHEMBL7573389 | 0.81 | MEN1 (0.49) | MAPTMEN1KMT2AHTTKDM4E | |
| SCHEMBL7571819 | 0.80 | CYP1A2 (0.39) | MAPTMEN1KMT2AHTTMITF | |
| SCHEMBL7571823 | 0.80 | CYP1A2 (0.39) | MAPTMEN1KMT2AHTTMITF | |
| SCHEMBL7573298 | 0.78 | CA2 (0.38) | L3MBTL1CA2LMNACA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810199-B1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5756769-A | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0810199-A1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |