Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 17/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6846804 | 0.90 | P2RX3 (0.53) | P2RX3MCL1 | |
| SCHEMBL6846802 | 0.90 | P2RX3 (0.53) | P2RX3MCL1 | |
| SCHEMBL3263994 | 0.89 | P2RX3 (0.63) | P2RX3MCL1 | |
| SCHEMBL25365111 | 0.88 | P2RX3 (0.53) | P2RX3MCL1 | |
| SCHEMBL12442648 | 0.87 | P2RX3 (0.52) | P2RX3MCL1 | |
| SCHEMBL18754654 | 0.87 | P2RX3 (0.52) | P2RX3MCL1 | |
| SCHEMBL6770355 | 0.87 | MCL1 (0.52) | P2RX3MCL1 | |
| SCHEMBL29523156 | 0.87 | P2RX3 (0.52) | P2RX3MCL1 | |
| SCHEMBL18617461 | 0.87 | P2RX3 (0.52) | P2RX3MCL1 | |
| SCHEMBL6770357 | 0.87 | MCL1 (0.52) | P2RX3MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002072087-A1 | PCRA HELICASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-09-19 | — | — | WO | disclosed |