Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LSS | P48449 | 2/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | CCR4 | P51679 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | PHGDH | O43175 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9949604 | 0.98 | HRH4 (0.37) | HRH4HRH3GRIN2BLSSSLC18A3 | |
| SCHEMBL17743426 | 0.96 | HRH4 (0.40) | HRH4HRH3MAPTSLC18A3KMT2A | |
| SCHEMBL1131900 | 0.96 | HRH4 (0.40) | HRH4HRH3MAPTSLC18A3KMT2A | |
| SCHEMBL17743406 | 0.93 | LSS (0.34) | HRH4HRH3GRIN2BMAPTLSS | |
| SCHEMBL13306227 | 0.93 | — | — | |
| SCHEMBL16822366 | 0.91 | HRH4 (0.36) | HRH4HRH3GRIN2BLSSSLC18A3 | |
| SCHEMBL11064526 | 0.89 | HRH4 (0.39) | HRH4HRH3LSSSLC18A3KMT2A | |
| SCHEMBL17743437 | 0.89 | HRH4 (0.39) | HRH4HRH3LSSSLC18A3KMT2A | |
| SCHEMBL17743439 | 0.89 | HRH4 (0.39) | HRH4HRH3LSSSLC18A3KMT2A | |
| SCHEMBL11067339 | 0.87 | SIGMAR1 (0.41) | HRH4HRH3LSSKMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382925-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMA (US) | 2023-11-30 | — | — | US | disclosed |
| EP-3442947-B1 | AMINE-SUBSTITUTED ARYL OR HETEROARYL COMPOUNDS AS EHMT1 AND EHMT2 INHIBITORS | EPIZYME INC (US) | 2023-06-07 | — | — | EP | disclosed |
| EP-3020464-B1 | ACIDIC GAS ABSORBING AGENT, METHOD FOR REMOVING ACIDIC GAS AND APPARATUS FOR REMOVING ACIDIC GAS | TOSHIBA KK (JP) | 2019-10-02 | — | — | EP | disclosed |
| CN-105597492-B | The removing method and sour gas removing device of acid gas absorbent, sour gas | 株式会社东芝 | 2018-11-16 | — | — | CN | disclosed |
| US-9446346-B2 | Acidic gas absorbing agent, method for removing acidic gas and apparatus for removing acidic gas | KABUSHIKI KAISHA TOSHIBA (JP) | 2016-09-20 | — | — | US | disclosed |
| CN-105597492-A | Acidic gas absorbing agent, method for removing acidic gas and apparatus for removing acidic gas | TOSHIBA KK | 2016-05-25 | — | — | CN | disclosed |
| US-20160136568-A1 | ACIDIC GAS ABSORBING AGENT, METHOD FOR REMOVING ACIDIC GAS AND APPARATUS FOR REMOVING ACIDIC GAS | KABUSHIKI KAISHA TOSHIBA (JP) | 2016-05-19 | — | — | US | disclosed |
| EP-3020464-A1 | ACIDIC GAS ABSORBING AGENT, METHOD FOR REMOVING ACIDIC GAS AND APPARATUS FOR REMOVING ACIDIC GAS | Kabushiki Kaisha Toshiba (JP) | 2016-05-18 | — | — | EP | disclosed |
| WO-2002092577-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2002-11-21 | — | — | WO | disclosed |
| WO-2002092578-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2002-11-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382925-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | CFTR, SCNN1G, SCNN1B | HRH4 2334/4885HRH3 4443/4885GRIN2B 4510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.