Bifenox

Bifenox

SCHEMBL7581046

CCNc1nc(Cl)nc(NC(C)(C)C#N)n1.COC(=O)c1cc(Oc2ccc(Cl)cc2Cl)ccc1[N+](=O)[O-].CP(=O)(O)CCC(N)C(=O)O

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.49
GRM4 Q14833 13/20 0.34
GRM8 O00222 12/20 0.34
GRM6 O15303 6/20 0.34
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
TTR P02766 1/20 0.34
PPOX P50336 1/20 0.34
GRM7 Q14831 2/20 0.31
HTT P42858 2/20 0.31
KDM4E B2RXH2 1/20 0.31
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HSD17B10 Q99714 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bifenox SCHEMBL7575772 0.94 TDP1 (0.52) TDP1GRM4GRM8GRM6KMT2A
Bifenox SCHEMBL7586481 0.93 TDP1 (0.57) TDP1GRM4GRM8GRM6KMT2A
Bifenox SCHEMBL7588484 0.89 TDP1 (0.53) TDP1GRM4GRM8GRM6KMT2A
Bifenox SCHEMBL7585742 0.89 TDP1 (0.62) TDP1KMT2AMEN1TTRPPOX
Acifluorfen SCHEMBL7584131 0.89 TDP1 (0.50) TDP1GRM4GRM8GRM6KMT2A
Bifenox SCHEMBL7586506 0.88 TDP1 (0.49) TDP1GRM4GRM8GRM6KMT2A
Lactofen SCHEMBL7581588 0.86 TDP1 (0.41) TDP1GRM4GRM8GRM6KMT2A
Bifenox SCHEMBL7576725 0.86 TDP1 (0.51) TDP1KMT2AMEN1TTRPPOX
Fomesafen SCHEMBL7575755 0.86 TDP1 (0.42) TDP1GRM4GRM8GRM6KMT2A
Oxyfluorfen SCHEMBL7589864 0.85 MEN1 (0.40) TDP1GRM4GRM8GRM6KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885GRM4 3673/4885GRM8 3918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.