Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | NGFR | P08138 | 1/20 | 0.41 |
| ▸ | ULK1 | O75385 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 4/20 | 0.39 |
| ▸ | JAK1 | P23458 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016427 | 0.82 | SMN1; SMN2 (0.53) | LMNAHPGDGSK3BAXLULK1 | |
| SCHEMBL11756961 | 0.81 | PDPK1 (0.51) | LMNAHPGDCYP2C19GSK3BAXL | |
| SCHEMBL3363383 | 0.81 | LMNA (0.49) | LMNAHPGDGSK3BALDH1A1MAPT | |
| SCHEMBL14979246 | 0.81 | TSHR (0.54) | LMNAHPGDALDH1A1MAPTKDM4E | |
| SCHEMBL30965223 | 0.81 | TSHR (0.54) | LMNAHPGDALDH1A1MAPTKDM4E | |
| SCHEMBL3589720 | 0.80 | GSK3B (0.47) | HPGDGSK3BAXLULK1ALDH1A1 | |
| SCHEMBL10931244 | 0.80 | LMNA (0.48) | LMNAHPGDGSK3BALDH1A1MAPT | |
| SCHEMBL10927575 | 0.80 | LMNA (0.48) | LMNAHPGDGSK3BALDH1A1MAPT | |
| SCHEMBL4215847 | 0.78 | GSK3B (0.49) | HPGDGSK3BAXLALDH1A1MAPT | |
| SCHEMBL30965201 | 0.78 | KDM4E (0.57) | LMNAHPGDGSK3BALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0904769-B1 | Keratin fibre dye compositions containing Indazole amine derivatives and dyeing method | OREAL (FR) | 2002-09-25 | — | — | EP | claimed |
| US-6027538-A | OXIDATION DYEING OF KERATINOUS FIBERS CONTAINING AT LEAST ONE COUPLER SELECTED FROM INDAZOLEAMINE DERIVATIVES AND AT LEAST ONE OXIDATION BASE; POWERFUL, NOT VERY SELECTIVE HAIR DYES WHICH ARE CAPABLE OF GENERATING INTENSE COLOR | L'OREAL S.A. (FR) | 2000-02-22 | — | — | US | disclosed |