Desmedipham

Desmedipham

SCHEMBL7581368

CCOC(=O)Nc1cccc(OC(=O)Nc2ccccc2)c1.COC(=O)c1cc(Oc2ccc(Cl)cc2Cl)ccc1[N+](=O)[O-]

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.64
MEN1 O00255 5/20 0.45
KMT2A Q03164 5/20 0.45
ALDH1A1 P00352 4/20 0.44
LMNA P02545 5/20 0.44
MAPT P10636 5/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
POLB P06746 2/20 0.42
MTNR1B P49286 1/20 0.41
TTR P02766 1/20 0.41
PPOX P50336 1/20 0.41
F9 P00740 1/20 0.41
HPGD P15428 2/20 0.41
RAB9A P51151 2/20 0.41
NPC1 O15118 1/20 0.41
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
HSP90AA1 P07900 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
MAPK1 P28482 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenmedipham SCHEMBL7586962 0.88 TDP1 (0.67) TDP1MEN1KMT2AALDH1A1LMNA
Acifluorfen SCHEMBL7582925 0.84 TDP1 (0.64) TDP1MEN1KMT2AALDH1A1LMNA
Desmedipham SCHEMBL7577677 0.84 MEN1 (0.53) TDP1MEN1KMT2AALDH1A1LMNA
Bifenox SCHEMBL7578846 0.80 TDP1 (0.64) TDP1MEN1KMT2AALDH1A1LMNA
Oxyfluorfen SCHEMBL7579696 0.80 MEN1 (0.51) TDP1MEN1KMT2AALDH1A1LMNA
Bifenox SCHEMBL8541647 0.80 TDP1 (1.00) TDP1MEN1KMT2AALDH1A1LMNA
Bifenox SCHEMBL38816 0.80 TDP1 (1.00) TDP1MEN1KMT2AALDH1A1LMNA
Bifenox SCHEMBL30862569 0.80 TDP1 (1.00) TDP1MEN1KMT2AALDH1A1LMNA
SCHEMBL9852597 0.79 TDP1 (0.78) TDP1MEN1KMT2AALDH1A1LMNA
Bifenox SCHEMBL28419037 0.79 TDP1 (0.98) TDP1MEN1KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885MEN1 4274/4885KMT2A 2099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.