Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 9/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.56 |
| ▸ | PARP11 | Q9NR21 | 5/20 | 0.56 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13998034 | 0.82 | PARP10 (0.55) | PARP1PARP10PARP11TRPM2 | |
| SCHEMBL29688148 | 0.81 | PARP1 (0.63) | PARP1PARP10PARP11TRPM2ACHE | |
| SCHEMBL437787 | 0.81 | PARP1 (0.63) | PARP1PARP10PARP11TRPM2ACHE | |
| SCHEMBL6687227 | 0.80 | MAPK1 (0.41) | PARP1ACHE | |
| SCHEMBL941425 | 0.78 | ALDH1A1 (0.46) | ACHE | |
| SCHEMBL7581574 | 0.78 | PARP1 (0.58) | PARP1PARP10PARP11TRPM2 | |
| SCHEMBL18757309 | 0.78 | PARP1 (0.58) | PARP1PARP10PARP11TRPM2ACHE | |
| SCHEMBL11805157 | 0.76 | MRGPRX4 (0.52) | ACHE | |
| SCHEMBL7582536 | 0.75 | PARP1 (0.62) | PARP1PARP10PARP11TRPM2 | |
| SCHEMBL6922984 | 0.75 | PARP1 (0.58) | PARP1PARP10PARP11ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348475-B1 | POLYMERASE INHIBITOR | GUILFORD PHARMACEUTICALS INC. | 2002-02-19 | — | — | US | disclosed |
| US-20020019417-A1 | Methods, compounds and compositions for treating gout | EISAI INC. | 2002-02-14 | — | — | US | disclosed |
| US-5177075-A | Antitumor agents | WARNER-LAMBERT COMPANY (US) | 1993-01-05 | — | — | US | disclosed |
| EP-0355750-A1 | Substituted dihydroisoquinolinones and related compounds as potentiators of the lethal effects of radiation and certain chemotherapeutic agents; selected compounds, analogs and process | WARNER-LAMBERT COMPANY (US) | 1990-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019417-A1 | Methods, compounds and compositions for treating gout | PARP2, PARP1, PARP3 | PARP1 2/4885PARP10 15/4885PARP11 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.