Aclonifen

Aclonifen

SCHEMBL7581698

CS(=O)(=O)c1cc(Cl)ccc1C(=O)c1cnoc1C1CC1.Nc1c([N+](=O)[O-])ccc(Oc2ccccc2)c1Cl.O=C(O)CNCP(=O)(O)O

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
TTR P02766 1/20 0.39
ALB P02768 1/20 0.39
THRB P10828 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
LMNA P02545 1/20 0.33
BCL2 P10415 2/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aclonifen SCHEMBL7586934 0.94 MEN1 (0.38) MEN1KMT2ATTRALBTHRB
Isoxaflutole SCHEMBL7585745 0.93 MEN1 (0.38) MEN1KMT2ATTRALBTHRB
Aclonifen SCHEMBL7580020 0.91 TDP1 (0.48) MEN1KMT2ATTRALBTHRB
Isoxaflutole SCHEMBL7584172 0.88 TDP1 (0.36) MEN1KMT2ATTRALBTHRB
Aclonifen SCHEMBL7578008 0.86 MEN1 (0.38) MEN1KMT2ATTRALBTHRB
Bifenox SCHEMBL7579301 0.85 TDP1 (0.49) MEN1KMT2ATTRTDP1LMNA
Isoxaflutole SCHEMBL7581122 0.83 TDP1 (0.45) MEN1KMT2ATTRALBTHRB
Acifluorfen SCHEMBL7575603 0.83 TDP1 (0.49) MEN1KMT2ATTRTHRBTDP1
Oxyfluorfen SCHEMBL7581499 0.81 MEN1 (0.40) MEN1KMT2ATTRTHRBTDP1
Fomesafen SCHEMBL7582126 0.81 TDP1 (0.43) MEN1KMT2ATTRTHRBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT MEN1 4274/4885KMT2A 2099/4885TTR 1945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.