Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 19/20 | 0.51 |
| ▸ | FNTB | P49356 | 19/20 | 0.51 |
| ▸ | PGGT1B | P53609 | 16/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5551495 | 0.83 | FNTA (0.50) | FNTAFNTBPGGT1B | |
| SCHEMBL3499079 | 0.83 | FNTA (0.56) | FNTAFNTBPGGT1B | |
| SCHEMBL7159262 | 0.77 | FNTA (0.67) | FNTAFNTBPGGT1B | |
| SCHEMBL7685251 | 0.75 | FNTA (0.61) | FNTAFNTBPGGT1B | |
| SCHEMBL5548038 | 0.74 | FNTA (0.62) | FNTAFNTBPGGT1B | |
| SCHEMBL7665146 | 0.73 | FNTA (0.73) | FNTAFNTBPGGT1B | |
| SCHEMBL7683462 | 0.70 | FNTA (0.61) | FNTAFNTBPGGT1B | |
| SCHEMBL7684988 | 0.69 | FNTA (0.61) | FNTAFNTBPGGT1B | |
| SCHEMBL7682385 | 0.69 | FNTA (0.61) | FNTAFNTBPGGT1B | |
| SCHEMBL7687123 | 0.69 | FNTA (0.61) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165082-A4 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2002-06-12 | — | — | EP | disclosed |
| EP-1165082-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000051611-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2000-09-08 | — | — | WO | disclosed |