Flumioxazin

Flumioxazin

SCHEMBL7581874

C#CCN1C(=O)COc2cc(F)c(N3C(=O)C4=C(CCCC4)C3=O)cc21.C=CCN(CC=C)C(=O)C(Cl)Cl.CCc1cccc(C)c1N(C(=O)CCl)C(C)COC

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flumioxazin SCHEMBL7579694 0.93 MEN1 (0.30) MEN1ALDH1A1KMT2ASMN1; SMN2
Flumioxazin SCHEMBL7581870 0.92 MEN1 (0.38) MEN1ALDH1A1KMT2ASMN1; SMN2MAPT
Flumioxazin SCHEMBL7579713 0.92
Flumioxazin SCHEMBL7577111 0.91
Flumioxazin SCHEMBL7589158 0.89 TP53 (0.40) ALDH1A1
Flumioxazin SCHEMBL7584516 0.89 TP53 (0.37)
Flumioxazin SCHEMBL7586293 0.85 MEN1 (0.33) MEN1ALDH1A1KMT2ASMN1; SMN2MAPT
Flumioxazin SCHEMBL7581634 0.85 MEN1 (0.34) MEN1ALDH1A1KMT2ASMN1; SMN2MAPT
Flumioxazin SCHEMBL7578419 0.84 MEN1 (0.33) MEN1ALDH1A1KMT2ASMN1; SMN2MAPT
Flumipropyn SCHEMBL7578792 0.84 MEN1 (0.35) MEN1ALDH1A1KMT2ASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT MEN1 4274/4885ALDH1A1 812/4885KMT2A 2099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.