Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.30 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.30 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.30 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7583487 | 0.93 | ABCC9 (0.32) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7582171 | 0.91 | — | — | |
| SCHEMBL7566911 | 0.88 | ABCC9 (0.34) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL13054725 | 0.88 | ABCC9 (0.34) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7589338 | 0.86 | AR (0.32) | — | |
| SCHEMBL7585494 | 0.86 | — | — | |
| SCHEMBL18294770 | 0.86 | — | — | |
| SCHEMBL7588792 | 0.84 | CCR6 (0.31) | — | |
| SCHEMBL7580668 | 0.84 | P2RX7 (0.33) | — | |
| SCHEMBL7582095 | 0.84 | MEN1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183252-B2 | Heterocyclic aspartyl protease inhibitors | SCHERING CORPORATION (US) | 2012-05-22 | — | — | US | disclosed |