Flumioxazin

Flumioxazin

SCHEMBL7582349

C#CCN1C(=O)COc2cc(F)c(N3C(=O)C4=C(CCCC4)C3=O)cc21.CC1(C)CON(Cc2ccccc2Cl)C1=O.C[S+](C)C.O=C(O)CNCP(=O)([O-])O

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.33
MAPT P10636 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
GRM7 Q14831 1/20 0.32
GRM4 Q14833 1/20 0.32
BRD4 O60885 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flumioxazin SCHEMBL7589902 0.94 GRM7 (0.34) TP53MAPTMEN1KMT2AGRM7
Flumioxazin SCHEMBL7581161 0.88 TSHR (0.39) MEN1KMT2AGRM7GRM4BRD4
Flumioxazin SCHEMBL7579042 0.86 GRM7 (0.36) GRM7GRM4
Flumipropyn SCHEMBL7578798 0.84 GRM7 (0.34) GRM7GRM4BRD4
Flumioxazin SCHEMBL7579276 0.84 GRM4 (0.32) TP53MAPTMEN1KMT2AGRM7
Clomazone SCHEMBL7579542 0.83 TP53 (0.31) TP53MAPT
Flumioxazin SCHEMBL7584341 0.81 GRM7 (0.33) GRM7GRM4
Flumioxazin SCHEMBL7587064 0.80 GRM7 (0.33) GRM7GRM4
Flumiciorac-Pentyl SCHEMBL7579959 0.79 PPOX (0.34) GRM7GRM4BRD4
Flumioxazin SCHEMBL7578756 0.79 TP53 (0.35) TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TP53 4303/4885MAPT 1092/4885MEN1 4274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.