Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.66 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | G6PD | P11413 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16745369 | 0.80 | MEN1 (0.53) | KMT2AMEN1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL7598789 | 0.80 | ALDH1A1 (0.62) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL29254055 | 0.80 | MEN1 (1.00) | KMT2AMEN1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL7574784 | 0.79 | F2 (0.47) | KMT2AMEN1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL14832762 | 0.78 | CYP2C9 (0.67) | KMT2AMEN1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL21530804 | 0.78 | CYP2C9 (0.67) | KMT2AMEN1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL2488262 | 0.77 | TDP1 (0.51) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL7575664 | 0.77 | ALDH1A1 (0.61) | KMT2AMEN1MAPTHTTATM | |
| SCHEMBL13240794 | 0.77 | TDP1 (0.51) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL13282701 | 0.77 | POLB (0.67) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |