Chlorsulfuron

Chlorsulfuron

SCHEMBL7582744

COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2Cl)n1.Cc1nn(-c2cc(NS(C)(=O)=O)c(Cl)cc2Cl)c(=O)n1C(F)F.O=C(O)COc1ccc(Cl)c2cccnc12

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PPOX P50336 1/20 0.46
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 1/20 0.35
NPC1 O15118 1/20 0.35
PTGER4 P35408 1/20 0.33
PKM P14618 1/20 0.32
MAPT P10636 1/20 0.31
USP2 O75604 1/20 0.30
GAA P10253 1/20 0.30
MAPK1 P28482 1/20 0.30
HSD17B10 Q99714 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfentrazone SCHEMBL7579247 0.95 PPOX (0.44) PPOXALDH1A1KDM4ENPC1PKM
Logran SCHEMBL7586332 0.94 PPOX (0.43) PPOXPKMMAPT
Prosulfuron SCHEMBL7576165 0.93 PPOX (0.42) PPOXPTGER4
Iodosulfuron SCHEMBL7583764 0.92 PPOX (0.43) PPOXPKM
Sulfentrazone SCHEMBL7585782 0.92 PPOX (0.43) PPOXPKM
Chlorsulfuron SCHEMBL7590529 0.88 PPOX (0.59) PPOXALDH1A1KDM4ENPC1MAPT
Sulfentrazone SCHEMBL7581248 0.87 PPOX (0.43) PPOXPKM
Sulfentrazone SCHEMBL7574348 0.86 PPOX (0.43) PPOXALDH1A1KDM4ENPC1PTGER4
Sulfentrazone SCHEMBL14655262 0.86 PPOX (0.62) PPOXKDM4EPKMMAPTGAA
Sulfentrazone SCHEMBL7597451 0.85 PPOX (0.48) PPOXKDM4EPKMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT PPOX 1/4885ALDH1A1 812/4885KDM4E 1886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.