Formaldehyde

Formaldehyde

SCHEMBL7583067

C=O.Nc1cccc(O)c1S(=O)(=O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AURKA O14965 1/20 0.46
AURKB Q96GD4 1/20 0.46
TTR P02766 1/20 0.44
TSHR P16473 3/20 0.43
ALOX15 P16050 1/20 0.43
ALDH1A1 P00352 3/20 0.41
HSD17B10 Q99714 2/20 0.41
TDP1 Q9NUW8 1/20 0.38
CA2 P00918 3/20 0.38
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA9 Q16790 2/20 0.38
DAPK1 P53355 1/20 0.38
CYP2C9 P11712 1/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA7 P43166 1/20 0.38
CA14 Q9ULX7 1/20 0.38
CA5B Q9Y2D0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1755214 0.96 AURKA (0.49) AURKAAURKBTTRTSHRALOX15
SCHEMBL17262957 0.83 ALDH1A1 (0.51) AURKAAURKBTTRTSHRALOX15
SCHEMBL668652 0.83 TTR (0.54) AURKAAURKBTTRTSHRALOX15
SCHEMBL9584262 0.81 ALOX15 (0.48) AURKAAURKBTTRTSHRALOX15
SCHEMBL28407130 0.81 TTR (0.52) AURKAAURKBTTRTSHRALOX15
SCHEMBL11430380 0.81 TTR (0.52) AURKAAURKBTTRTSHRALOX15
SCHEMBL582872 0.80 ALDH1A1 (0.43) AURKAAURKBTTRTSHRALOX15
SCHEMBL28506092 0.79 ALOX15 (0.46) AURKAAURKBTTRTSHRALOX15
SCHEMBL5432881 0.78 AURKA (0.41) AURKAAURKBTTRTSHRALOX15
SCHEMBL11869206 0.78 TSHR (0.44) AURKAAURKBTTRTSHRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0816298-B1 Agents for and method of reducing the fluidity drop of hydraulic cement compositions and method of producing such agents TAKEMOTO OIL & FAT CO LTD (JP) 2002-10-02 EP disclosed
US-5919881-A USING WATER SOLUBLE VINYL COPOLYMER TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) 1999-07-06 US disclosed
EP-0816298-A1 Agents for and method of reducing the fluidity drop of hydraulic cement compositions and method of producing such agents Takemoto Yushi Kabushiki Kaisha (JP) 1998-01-07 EP disclosed