Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900832 | 0.73 | MEN1 (0.37) | HPGDKDM4EALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL1719339 | 0.71 | HPGD (0.44) | HPGDKDM4EALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL10419448 | 0.70 | HPGD (0.40) | HPGDKDM4EALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL9683566 | 0.69 | NPSR1 (0.33) | HPGDKDM4EALDH1A1SMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL1925195 | 0.66 | ALDH1A1 (0.95) | HPGDKDM4EALDH1A1SMN1; SMN2CA12 | |
| 2,2'-Dihydroxybenzphenone SCHEMBL18422 | 0.65 | HPGD (0.67) | HPGDKDM4EALDH1A1SMN1; SMN2CA12 | |
| 2,2'-Dihydroxybenzphenone SCHEMBL29572496 | 0.65 | HPGD (0.67) | HPGDKDM4EALDH1A1SMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL11324199 | 0.64 | ALDH1A1 (0.90) | HPGDKDM4EALDH1A1SMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL1509155 | 0.64 | ALDH1A1 (1.00) | HPGDKDM4EALDH1A1SMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL1967 | 0.64 | ALDH1A1 (1.00) | HPGDKDM4EALDH1A1SMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263454-A2 | METHODS FOR ENHANCING THE BIOAVAILABILITY OF A DRUG | Praecis Pharmaceuticals Incorporated (US) | 2002-12-11 | — | — | EP | disclosed |
| WO-2000052048-A9 | MODULATORS OF BETA-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | PRAECIS PHARM INC (US) | 2002-04-11 | — | — | WO | disclosed |
| WO-2001058470-A2 | METHODS FOR ENHANCING THE BIOAVAILABILITY OF A DRUG | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2001-08-16 | — | — | WO | disclosed |