SCHEMBL9683566

SCHEMBL9683566

CC1(c2ccccc2O)C=CC(C(=O)O)C=C1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.33
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA7 P43166 2/20 0.33
CA9 Q16790 2/20 0.33
CA14 Q9ULX7 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HMGB1 P09429 1/20 0.33
HPGD P15428 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NAPRT Q6XQN6 1/20 0.33
HSD11B1 P28845 3/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL900832 0.81 MEN1 (0.37) NPSR1CA12CA1CA2CA7
SCHEMBL9683216 0.81 TSHR (0.35) CA12CA1CA2CA7CA9
SCHEMBL5696701 0.80 HTT (0.42) CA12CA1CA2CA7CA9
SCHEMBL20594620 0.74 CYSLTR2 (0.45) THRB
SCHEMBL2433668 0.73 MEN1 (0.38) ALDH1A1MEN1KMT2A
SCHEMBL9127364 0.70 CYP3A4 (0.34) NPSR1CA1CA2KDM4EALDH1A1
SCHEMBL9683488 0.70 GRIN2B (0.40) CRHBPCRHR2OPRM1OPRK1OPRD1
SCHEMBL7583146 0.69 HPGD (0.44) CA12CA1CA2CA7CA9
SCHEMBL20594607 0.67 CYP2D6 (0.40) CRHBPCRHR2AKR1B1
SCHEMBL11527286 0.67 HDAC4 (0.39) HSD11B1CRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5089590-A LIQUID CRYSTALLINE COMPOUNDS, THEIR PRODUCTION AND THEIR USE AS MODIFIERS FOR POLYCARBONATES, POLYESTER CARBONATES AND POLYESTERS BAYER AKTIENGESELLSCHAFT (DE) 1992-02-18 US disclosed
US-5084549-A Aromatic polyesters as thermoplastic molding materials BAYER AKTIENGESELLSCHAFT (DE) 1992-01-28 US disclosed