Primisulfuron

Primisulfuron

SCHEMBL7583178

CCOC(=O)C(Cl)Cc1cc(-n2nc(C)n(C(F)F)c2=O)c(F)cc1Cl.COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2CCC(F)(F)F)n1.O=C(Nc1nc(OC(F)F)cc(OC(F)F)n1)NS(=O)(=O)c1ccccc1C(=O)O

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.32
KDM4E B2RXH2 1/20 0.30
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
DHODH Q02127 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Primisulfuron SCHEMBL7584287 0.94
Primisulfuron SCHEMBL7588772 0.93
Prosulfuron SCHEMBL7586893 0.92 MAPT (0.35) MAPTKDM4ENPC1ALDH1A1DHODH
Primisulfuron SCHEMBL7588338 0.92
Carfentrazone-Ethyl SCHEMBL7582144 0.90 MAPT (0.38) MAPTKDM4ENPC1ALDH1A1DHODH
Primisulfuron SCHEMBL7580828 0.89 MAPT (0.36) MAPTKDM4ENPC1ALDH1A1DHODH
Prosulfuron SCHEMBL7581307 0.89 MAPT (0.33) MAPTKDM4ENPC1ALDH1A1
Rimsulfuron SCHEMBL7589453 0.88 MAPT (0.31) MAPTKDM4ENPC1ALDH1A1
Nicosulfuron SCHEMBL7576520 0.87 CDK1 (0.32) MAPT
Prosulfuron SCHEMBL7580107 0.87 MAPT (0.32) MAPTKDM4ENPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT MAPT 1092/4885KDM4E 1886/4885NPC1 4238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.