Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7580732 | 0.95 | MCHR1 (0.49) | MCHR1CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL7585532 | 0.94 | MCHR1 (0.50) | MCHR1CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL7575843 | 0.92 | MCHR1 (0.47) | MCHR1CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL557732 | 0.86 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL558137 | 0.77 | ALDH1A1 (0.49) | MCHR1ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL5756170 | 0.76 | NPC1 (0.36) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL5760823 | 0.74 | GAA (0.39) | CYP1A2CYP2C9CYP2C19ALDH1A1KDM4E | |
| SCHEMBL2522116 | 0.74 | BID (0.40) | KDM4EMAPTTLR8 | |
| SCHEMBL557496 | 0.73 | MCHR1 (0.44) | MCHR1ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL6689421 | 0.73 | ALDH1A1 (0.52) | MCHR1CYP1A2CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882730-B1 | PHOSPHONIC ACID DIESTER DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 2002-10-02 | — | — | EP | disclosed |
| US-5985858-A | TREATING AND PREVENTING HYPERLIPIDEMIA, DIABETES AND CATARACT, OR AS AN ANTITUMOR AGENT | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0882730-A1 | PHOSPHONIC ACID DIESTER DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1998-12-09 | — | — | EP | disclosed |