Nicosulfuron

Nicosulfuron

SCHEMBL7583522

CCNc1nc(Cl)nc(NC(C)C)n1.COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2ncccc2C(=O)N(C)C)n1.CP(=O)(O)CCC(N)C(=O)O.Nc1c([N+](=O)[O-])ccc(Oc2ccccc2)c1Cl

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 3/20 0.31
GRM4 Q14833 3/20 0.31
GRM6 O15303 2/20 0.31
MEN1 O00255 1/20 0.31
TTR P02766 1/20 0.31
ALB P02768 1/20 0.31
THRB P10828 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CDK1 P06493 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nicosulfuron SCHEMBL7588595 0.93 TDP1 (0.35) MEN1TTRALBTHRBKMT2A
Nicosulfuron SCHEMBL7589032 0.92 GRM8 (0.36) GRM8GRM4GRM6MEN1TTR
Nicosulfuron SCHEMBL7574970 0.91 CDK1 (0.32) MEN1TTRALBTHRBKMT2A
Nicosulfuron SCHEMBL7583949 0.90
Nicosulfuron SCHEMBL7584989 0.89 TDP1 (0.38) GRM8GRM4GRM6TDP1
Nicosulfuron SCHEMBL7575948 0.87 MEN1 (0.38) MEN1TTRKMT2ATDP1
Primisulfuron SCHEMBL7580251 0.87 CDK1 (0.33) GRM8GRM4GRM6MEN1TTR
Nicosulfuron SCHEMBL7584534 0.87 MEN1 (0.32) MEN1TTRKMT2ATDP1
Nicosulfuron SCHEMBL7578173 0.86 MEN1 (0.34) MEN1TTRKMT2ATDP1
Rimsulfuron SCHEMBL7578982 0.84 MEN1 (0.37) GRM8GRM4GRM6MEN1TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT GRM8 3918/4885GRM4 3673/4885GRM6 2895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.