SCHEMBL7583527

SCHEMBL7583527

Nc1ccc2cc(S(=O)(=O)O)c(N=Nc3ccc(N=Nc4ccc(S(=O)(=O)O)cc4)c4ccccc34)c(O)c2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.55
THRB P10828 1/20 0.55
KMT2A Q03164 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
ENPP2 Q13822 6/20 0.54
CD40 P25942 1/20 0.53
CD40LG P29965 1/20 0.53
CYP1A2 P05177 3/20 0.51
CYP2C9 P11712 1/20 0.51
MAPK1 P28482 1/20 0.51
DNASE1L3 Q13609 1/20 0.51
PHLPP2 Q6ZVD8 1/20 0.51
ALDH1A1 P00352 1/20 0.50
HIF1A Q16665 1/20 0.50
ATIC P31939 1/20 0.49
CA2 P00918 1/20 0.48
CA3 P07451 1/20 0.48
SENP2 Q9HC62 3/20 0.48
SUMO2 P61956 2/20 0.48
SUMO1 P63165 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14608126 0.95 ENPP2 (0.54) MEN1THRBKMT2ATDP1ENPP2
SCHEMBL14608469 0.94 ENPP2 (0.57) MEN1THRBKMT2ATDP1ENPP2
SCHEMBL7591307 0.93 CD40 (0.55) MEN1THRBKMT2ATDP1ENPP2
SCHEMBL9331800 0.93 CD40 (0.55) MEN1THRBKMT2ATDP1ENPP2
SCHEMBL9400781 0.90 SENP2 (0.58) MEN1THRBKMT2ATDP1ENPP2
SCHEMBL9335047 0.89 MEN1 (0.58) MEN1THRBKMT2ATDP1ENPP2
SCHEMBL9335040 0.89 MEN1 (0.58) MEN1THRBKMT2ATDP1ENPP2
SCHEMBL8955236 0.89 ENPP2 (0.51) MEN1THRBKMT2ATDP1ENPP2
SCHEMBL26459974 0.89 MEN1 (0.58) MEN1THRBKMT2ATDP1ENPP2
SCHEMBL8955249 0.89 ENPP2 (0.51) MEN1THRBKMT2ATDP1ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0669381-B1 Dye, ink containing the same, and ink-jet recording method and instrument using the ink CANON KK (JP) 2002-09-11 EP disclosed
US-5733363-A WATER FASTNESS; SOLUTION SOLUBILITY CANON KABUSHIKI KAISHA (JP) 1998-03-31 US disclosed
EP-0669381-A2 Dye, ink containing the same, and ink-jet recording method and instrument using the ink CANON KABUSHIKI KAISHA (JP) 1995-08-30 EP disclosed