Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7588403 | 0.93 | — | — | |
| SCHEMBL18294773 | 0.91 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL7589121 | 0.91 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL7588172 | 0.89 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL18294771 | 0.89 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL13053891 | 0.88 | MEN1 (0.36) | MEN1KMT2AHTR7PGR | |
| SCHEMBL7553578 | 0.88 | MEN1 (0.36) | MEN1KMT2AHTR7PGR | |
| SCHEMBL7580536 | 0.84 | NPY5R (0.34) | MEN1KMT2A | |
| SCHEMBL7583745 | 0.84 | — | — | |
| SCHEMBL7579947 | 0.82 | TP53 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183252-B2 | Heterocyclic aspartyl protease inhibitors | SCHERING CORPORATION (US) | 2012-05-22 | — | — | US | disclosed |