Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18294770 | 0.92 | — | — | |
| SCHEMBL7585494 | 0.92 | — | — | |
| SCHEMBL7581116 | 0.91 | TP53 (0.31) | — | |
| SCHEMBL7582095 | 0.88 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL7588393 | 0.87 | P2RX7 (0.34) | MEN1KMT2A | |
| SCHEMBL7585732 | 0.86 | MEN1 (0.37) | NPY5RMEN1KMT2ASLC6A9RORC | |
| SCHEMBL13054488 | 0.86 | MEN1 (0.37) | NPY5RMEN1KMT2ASLC6A9RORC | |
| SCHEMBL7583487 | 0.85 | ABCC9 (0.32) | MEN1KMT2A | |
| SCHEMBL7588172 | 0.85 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL7589121 | 0.85 | MEN1 (0.35) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183252-B2 | Heterocyclic aspartyl protease inhibitors | SCHERING CORPORATION (US) | 2012-05-22 | — | — | US | disclosed |