Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 4/20 | 0.42 |
| ▸ | WNT3A | P56704 | 3/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | GPR183 | P32249 | 2/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL758623 | 0.86 | CTNNB1 (0.44) | CTNNB1WNT3ASMYD3KIF11GPR183 | |
| SCHEMBL1907961 | 0.80 | KDM4E (0.49) | CTNNB1WNT3ASMYD3KIF11BRAF | |
| SCHEMBL31085181 | 0.80 | KDM4E (0.49) | CTNNB1WNT3ASMYD3KIF11BRAF | |
| SCHEMBL5503013 | 0.79 | CTNNB1 (0.49) | CTNNB1WNT3ASMYD3KIF11CNR1 | |
| SCHEMBL24769914 | 0.79 | CTNNB1 (0.54) | CTNNB1WNT3ASMYD3GPR183PDK1 | |
| SCHEMBL5753071 | 0.78 | ALDH1A1 (0.52) | CTNNB1WNT3ASMYD3KIF11CNR1 | |
| SCHEMBL2647988 | 0.77 | CTNNB1 (0.55) | CTNNB1WNT3ASMYD3 | |
| SCHEMBL15104920 | 0.76 | TSHR (0.53) | CTNNB1WNT3ASMYD3KIF11PDK2 | |
| SCHEMBL758294 | 0.75 | KDM4E (0.47) | CTNNB1WNT3ASMYD3KIF11CNR1 | |
| SCHEMBL23336084 | 0.73 | CTNNB1 (0.40) | CTNNB1WNT3ASMYD3KIF11CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776011-B1 | FUNGICIDAL COMPOSITION CONTAINING AN ACID AMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-8039420-B2 | Fungicidal composition containing acid amide derivative | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2011-10-18 | — | — | US | disclosed |
| US-7829501-B2 | Fungicidal composition containing acid amide derivative | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-11-09 | — | — | US | disclosed |
| US-20100261735-A1 | FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-10-14 | — | — | US | disclosed |
| US-20100261675-A1 | FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-10-14 | — | — | US | disclosed |
| US-20080318779-A1 | N-[(4'-methoxy-2'-methyl-1,1-dimethyl)phenacyl]-3-methyl-2-thiophenecarboxamide and another fungicide or an antibiotic; controlling noxious fungi at a low dose; Oomycetes, Ascomycetes, Basidiomycetes, Deuteromycetes particularly effective against Ascomycetes or Deuteromycetes; plant diseases | ISHIHARA SANGYO KAISHA LTD (JP) | 2008-12-25 | — | — | US | disclosed |
| EP-1776011-A1 | FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006016708-A1 | FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2006-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318779-A1 | N-[(4'-methoxy-2'-methyl-1,1-dimethyl)phenacyl]-3-methyl-2-thiophenecarboxamide and another fungicide or an antibiotic; controlling noxious fungi at a low dose; Oomycetes, Ascomycetes, Basidiomycetes, Deuteromycetes particularly effective against Ascomycetes or Deuteromycetes; plant diseases | AADAC, NAT1, TH | CTNNB1 3551/4885WNT3A 2780/4885SMYD3 507/4885 |
| US-20100261675-A1 | FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE | CBR3, AADAC, NAT1 | CTNNB1 4680/4885WNT3A 4550/4885SMYD3 877/4885 |
| US-20100261735-A1 | FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE | CBR3, AADAC, NAT1 | CTNNB1 4680/4885WNT3A 4550/4885SMYD3 877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.