Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7584833 | 0.89 | SLC6A2 (0.32) | SLC6A2SLC6A4SLC6A3SIGMAR1KDM4E | |
| SCHEMBL7591693 | 0.88 | IGF1R (0.32) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7581145 | 0.88 | SLC6A2 (0.31) | SLC6A2SLC6A4SLC6A3SIGMAR1KDM4E | |
| SCHEMBL7581302 | 0.88 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3SIGMAR1KDM4E | |
| SCHEMBL7586137 | 0.83 | DRD2 (0.39) | KDM4EGAADRD2 | |
| SCHEMBL7591694 | 0.71 | DRD2 (0.39) | DRD2 | |
| SCHEMBL7584423 | 0.71 | DRD2 (0.39) | KDM4EGAADRD2 | |
| SCHEMBL7585900 | 0.70 | DRD2 (0.40) | KDM4EGAADRD2 | |
| SCHEMBL7582764 | 0.70 | DRD2 (0.38) | KDM4EGAADRD2 | |
| SCHEMBL7586573 | 0.69 | KDM4E (0.36) | KDM4EGAADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675118-B1 | Biphenylderivatives, process for their preparation and their use as medicaments | EISAI CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |