Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7574752 | 0.87 | NPSR1 (0.53) | KMT2AALDH1A1MAPTMEN1HTT | |
| SCHEMBL27940247 | 0.85 | SYK (0.50) | TDP1KMT2AALDH1A1MAPTTP53 | |
| SCHEMBL2482091 | 0.84 | SMN1; SMN2 (0.53) | KMT2AALDH1A1SMN1; SMN2FPR2MAPT | |
| SCHEMBL16786108 | 0.83 | CYP1A2 (0.45) | TDP1CYP2D6 | |
| SCHEMBL2483521 | 0.81 | FPR2 (0.49) | TDP1ALDH1A1SMN1; SMN2FPR2KDM4E | |
| SCHEMBL146704 | 0.81 | FPR2 (0.49) | TDP1ALDH1A1SMN1; SMN2FPR2KDM4E | |
| SCHEMBL2483519 | 0.81 | FPR2 (0.49) | TDP1ALDH1A1SMN1; SMN2FPR2KDM4E | |
| SCHEMBL3904896 | 0.81 | HPGD (0.48) | TDP1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7583934 | 0.80 | ALDH1A1 (0.49) | KMT2AALDH1A1SMN1; SMN2FPR2KDM4E | |
| SCHEMBL28534876 | 0.80 | FPR2 (0.47) | TDP1KMT2AALDH1A1SMN1; SMN2FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |