Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 4/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2572486 | 0.83 | — | — | |
| SCHEMBL29291158 | 0.80 | — | — | |
| SCHEMBL21004936 | 0.80 | ALDH1A1 (0.40) | — | |
| SCHEMBL7590352 | 0.80 | — | — | |
| SCHEMBL1351693 | 0.80 | CHRM2 (0.33) | — | |
| SCHEMBL27407047 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL27835399 | 0.78 | CHRM2 (0.33) | — | |
| SCHEMBL31031091 | 0.78 | CHRM2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL28060494 | 0.78 | CHRM2 (0.33) | — | |
| SCHEMBL19209920 | 0.78 | SLC6A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0803502-B1 | Process for the preparation of optically active piperazine-2-carboxylic acid derivatives | LONZA AG (CH) | 2002-06-26 | — | — | EP | disclosed |
| EP-0803502-A2 | Process for the preparation of optically active piperazine-2-carboxylic acid derivatives | LONZA AG (CH) | 1997-10-29 | — | — | EP | disclosed |