Urea

Urea

SCHEMBL758386

CC=C(CO)CO.NC(N)=O

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
ALDH1A1 P00352 1/20 0.38
OR51E2 Q9H255 1/20 0.38
ALOX15 P16050 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
GRIK1 P39086 1/20 0.31
GRIK2 Q13002 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL191502 0.83
Urea SCHEMBL8016733 0.75 ALDH1A1 (0.38) LMNATDP1ALDH1A1OR51E2
Urea SCHEMBL7643907 0.73 OR51E2 (0.35) LMNATDP1ALDH1A1OR51E2ALOX15
Urea SCHEMBL27886840 0.73 ALDH1A1 (0.35) LMNATDP1ALDH1A1OR51E2
Urea SCHEMBL7643901 0.73 OR51E2 (0.35) LMNATDP1ALDH1A1OR51E2ALOX15
Urea SCHEMBL2443503 0.69 ALDH1A1 (0.36) LMNATDP1ALDH1A1OR51E2
SCHEMBL29612204 0.69
Urea SCHEMBL322840 0.68
Urea SCHEMBL1064520 0.68
Urea SCHEMBL3384849 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 313 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115181468-B Super-hydrophilic self-cleaning coating sol and preparation method and application thereof 泉州师范学院 2024-03-05 CN claimed
CN-115874450-A Anti-shrinkage jean fabric and preparation method thereof 佛山市南海雄科纺织有限公司 2023-03-31 CN claimed
CN-115232528-A Super-hydrophilic antibacterial coating sol and preparation method and application thereof 泉州师范学院 2022-10-25 CN claimed
CN-115181468-A Super-hydrophilic self-cleaning coating sol and preparation method and application thereof 泉州师范学院 2022-10-14 CN claimed
EP-2873962-B1 Fixing of tissue samples using aldehyde-releasing compounds containing nitrogen LEICA BIOSYSTEMS NUSSLOCH GMBH (DE) 2020-09-02 EP claimed
US-10345202-B2 Fixing tissue samples using nitrogen-containing compounds that release aldehydes LEICA BIOSYSTEMS NUSSLOCH GMBH (DE) 2019-07-09 US claimed
EP-2823282-B1 FOMALIN FREE FIXATIVES FOR HISTOLOGICAL STAINING OF TISSUE SAMPLES GERIGK ROBERTO (DE) 2017-10-25 EP claimed
US-9562836-B2 Formalin-free fixation agent for histological stains of tissue samples Gerigk, Roberto (DE) 2017-02-07 US claimed
US-20150140601-A1 FIXING TISSUE SAMPLES USING NITROGEN-CONTAINING COMPOUNDS THAT RELEASE ALDEHYDES LEICA BIOSYSTEMS NUSSLOCH GMBH (DE) 2015-05-21 US claimed
US-20150050689-A1 Formalin-Free Fixation Agent For Histological Stains of Tissue Samples GERIGK, ROBERTO (DE) 2015-02-19 US claimed
EP-0268368-B1 Fabric treatment ALBRIGHT & WILSON UK LTD (GB) 1995-12-13 EP claimed
US-4657957-A Binding agent aqueous dispersions having improved coagulation properties SANDOZ LTD. (CH) 1987-04-14 US claimed
US-4438533-A FLOCK FIBERS WITH POLYMERIC BINDERS KUFNER TEXTILWERKE KG (DE) 1984-03-27 US claimed
US-4435442-A Method and apparatus for reinforcing face fabric materials for garments KUFNER TEXTILWERKE KG (DE) 1984-03-06 US claimed
US-4104444-A POLYETHOXYAMINES, MELAMINE DERIVATIVES HOECHST AKTIENGESELLSCHAFT (DE) 1978-08-01 US claimed
US-4092107-A WASH AND WEAR, CREASE RESISTANCE, SOIL RELEASE, ACRYLIC ESTER POLYMERS AKZONA INCORPORATED (US) 1978-05-30 US claimed
US-4088440-A Transfer printing of treated cellulosics HEBERLEIN TEXTILDRUCK AG (CH) 1978-05-09 US claimed
US-4002785-A IMPREGNATING A NONWOVEN WEB WITH AN AMIDE MIGRATION INHIBITOR AND A SYNTHETIC RESIN BINDER SANDOZ LTD. (CH) 1977-01-11 US claimed
US-3984367-A UREAS, ALDEHYDES, AMINES, PHOSPHORIC ACID PEARSON, GLENN A. 1976-10-05 US claimed
US-3983269-A CONDENSATION PRODUCT OF ALDEHYDE, AMINE AND INORGANIC ACID REACTED WITH UREA PEARSON, GLENN A. 1976-09-28 US claimed