SCHEMBL7583875

SCHEMBL7583875

Cl[Sc][SiH](CC1C=Cc2ccccc21)CC1C=Cc2ccccc21

nearest known ligand 0.45

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.45
HTR2A P28223 1/20 0.35
SIGMAR1 Q99720 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1539037 0.83 HTR6 (0.45) HTR6HTR2ASIGMAR1
SCHEMBL8569207 0.80 HTR6 (0.49) HTR6HTR2ASIGMAR1
SCHEMBL8568650 0.80 HTR6 (0.49) HTR6HTR2ASIGMAR1
SCHEMBL6909204 0.77 HTR6 (0.50) HTR6HTR2ASIGMAR1
SCHEMBL8161933 0.77 HTR6 (0.49) HTR6HTR2ASIGMAR1
SCHEMBL6910806 0.76 HTR6 (0.45) HTR6HTR2ASIGMAR1
SCHEMBL6911374 0.76 HTR6 (0.49) HTR6HTR2ASIGMAR1
SCHEMBL1453509 0.75 HTR6 (0.58) HTR6HTR2ASIGMAR1
SCHEMBL4652368 0.74 HTR6 (0.46) HTR6HTR2ASIGMAR1
SCHEMBL8964848 0.74 HTR6 (0.46) HTR6HTR2ASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1115730-B1 CATALYTIC PROCESS FOR ISOMERIZING METALLOCENES ALBEMARLE CORP (US) 2002-10-02 EP disclosed
EP-1115730-A1 CATALYTIC PROCESS FOR ISOMERIZING METALLOCENES ALBEMARLE CORPORATION (US) 2001-07-18 EP disclosed
WO-2000017213-A1 CATALYTIC PROCESS FOR ISOMERIZING METALLOCENES ALBEMARLE CORPORATION (US) 2000-03-30 WO disclosed
US-5965759-A Catalytic process for isomerizing metallocenes ALBEMARLE CORPORATION (US) 1999-10-12 US disclosed