Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4652368 | 0.79 | HTR6 (0.46) | HTR6RETSIGMAR1HTR2AKDM4E | |
| SCHEMBL8568650 | 0.78 | HTR6 (0.49) | HTR6RETSIGMAR1HTR2AKDM4E | |
| SCHEMBL8569207 | 0.78 | HTR6 (0.49) | HTR6RETSIGMAR1HTR2AKDM4E | |
| SCHEMBL8161933 | 0.78 | HTR6 (0.49) | HTR6RETSIGMAR1HTR2AKDM4E | |
| SCHEMBL7595592 | 0.78 | HTR6 (0.49) | HTR6RETSIGMAR1HTR2AKDM4E | |
| SCHEMBL13278806 | 0.78 | HTR6 (0.49) | HTR6RETSIGMAR1HTR2AKDM4E | |
| SCHEMBL7640895 | 0.77 | HTR6 (0.45) | HTR6RETSIGMAR1HTR2AKDM4E | |
| SCHEMBL1539037 | 0.77 | HTR6 (0.45) | HTR6RETSIGMAR1HTR2AKDM4E | |
| SCHEMBL8966167 | 0.77 | HTR6 (0.42) | HTR6RETSIGMAR1HTR2AKDM4E | |
| SCHEMBL1453509 | 0.76 | HTR6 (0.58) | HTR6RETSIGMAR1HTR2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539901-B1 | Process for producing thermoplastic resin | JAPAN SYNTHETIC RUBBER CO LTD (JP) | 1996-02-28 | — | — | EP | claimed |
| EP-0539901-A1 | Process for producing thermoplastic resin | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1993-05-05 | — | — | EP | claimed |
| EP-0539901-B1 | Process for producing thermoplastic resin | JAPAN SYNTHETIC RUBBER CO LTD (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5274053-A | Grafting a vinyl monomer to a modified polyorganosiloxane and crosslinking with an alkoxysilane having an azo or disulfide group | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1993-12-28 | — | — | US | disclosed |
| EP-0539901-A1 | Process for producing thermoplastic resin | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1993-05-05 | — | — | EP | disclosed |