SCHEMBL7584415

SCHEMBL7584415

CCOC(=O)COC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2c(Cl)nc3ccccn23)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
TTR P02766 1/20 0.41
PPOX P50336 1/20 0.41
THRB P10828 1/20 0.34
VDR P11473 1/20 0.34
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
MAPT P10636 4/20 0.33
HTT P42858 1/20 0.33
NTRK1 P04629 1/20 0.32
GAA P10253 1/20 0.32
LMNA P02545 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C19 P33261 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfosulfuron SCHEMBL7586832 0.94 MEN1 (0.40) MEN1KMT2ATDP1TTRPPOX
Lactofen SCHEMBL7588400 0.92 MEN1 (0.40) MEN1KMT2ATDP1TTRPPOX
Acifluorfen SCHEMBL7577278 0.90 TDP1 (0.53) MEN1KMT2ATDP1TTRPPOX
Oxyfluorfen SCHEMBL7580132 0.89 MEN1 (0.40) MEN1KMT2ATDP1TTRPPOX
Fomesafen SCHEMBL7588015 0.88 TDP1 (0.44) MEN1KMT2ATDP1TTRPPOX
Halosulfuron SCHEMBL7578309 0.88 MEN1 (0.45) MEN1KMT2ATDP1TTRPPOX
Sulfosulfuron SCHEMBL7577290 0.86 MEN1 (0.35) MEN1KMT2ATDP1TTRPPOX
Lactofen SCHEMBL7587278 0.86 TDP1 (0.39) MEN1KMT2ATDP1TTRPPOX
SCHEMBL7581595 0.86 TDP1 (0.47) MEN1KMT2ATDP1TTRPPOX
Chlorimuron Ethyl SCHEMBL7581150 0.86 TDP1 (0.44) MEN1KMT2ATDP1TTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT MEN1 4274/4885KMT2A 2099/4885TDP1 1969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.