Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL829552 | 0.87 | LMNA (0.40) | KDM4EMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL6758382 | 0.85 | KDM4E (0.45) | KDM4EMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL16176644 | 0.82 | LMNA (0.46) | KDM4EMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL10395475 | 0.82 | ALDH1A1 (0.55) | KDM4EMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL10395474 | 0.82 | ALDH1A1 (0.55) | KDM4EMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL829949 | 0.81 | KDM4E (0.48) | KDM4EMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL23934240 | 0.80 | GRIK1 (0.55) | KDM4EMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL375312 | 0.80 | GRIK1 (0.55) | KDM4EMEN1KMT2APOLBALDH1A1 | |
| Methacrylic Acid SCHEMBL2912337 | 0.80 | GRIK1 (0.49) | KDM4EMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL11428965 | 0.80 | KDM4E (0.51) | KDM4EMEN1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754452-B1 | Pharmaceutical preparation in form of coated capsule releasable at lower part of digestive tract | TANABE SEIYAKU CO (JP) | 2002-10-02 | — | — | EP | claimed |