Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955773 | 0.78 | SLC6A2 (0.34) | DRD2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1573576 | 0.66 | USP2 (0.50) | DRD2DRD3KCNH2 | |
| SCHEMBL10554729 | 0.63 | KDM4E (0.54) | DRD2KCNH2 | |
| SCHEMBL7591668 | 0.62 | CHRNA7 (0.46) | DRD3SIGMAR1HTR7 | |
| SCHEMBL10868169 | 0.61 | ALDH1A1 (0.44) | SIGMAR1 | |
| SCHEMBL7581145 | 0.60 | SLC6A2 (0.31) | DRD2DRD3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7581302 | 0.60 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL13187900 | 0.60 | ALDH1A1 (0.43) | SIGMAR1 | |
| SCHEMBL13187873 | 0.60 | ALDH1A1 (0.43) | DRD2DRD3 | |
| SCHEMBL10868745 | 0.60 | MC4R (0.56) | DRD2SIGMAR1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675118-B1 | Biphenylderivatives, process for their preparation and their use as medicaments | EISAI CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |