Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7581302 | 0.83 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3CCR1 | |
| SCHEMBL7582764 | 0.82 | DRD2 (0.38) | DRD2 | |
| SCHEMBL7586573 | 0.80 | KDM4E (0.36) | DRD2 | |
| SCHEMBL7582136 | 0.79 | DRD2 (0.33) | DRD2CCR1 | |
| SCHEMBL7582141 | 0.79 | KDM4E (0.38) | DRD2 | |
| SCHEMBL7581291 | 0.78 | KDM4E (0.40) | DRD2 | |
| SCHEMBL7581935 | 0.78 | KDM4E (0.40) | DRD2 | |
| SCHEMBL7584470 | 0.78 | DRD2 (0.33) | SLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL7585537 | 0.75 | DRD4 (0.48) | DRD2 | |
| SCHEMBL7585007 | 0.74 | MAPT (0.51) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281214-B1 | USEFUL FOR TREATING AND AMELIORATING MENTAL DISORDERS | EISAI CO., LTD (JP) | 2001-08-28 | — | — | US | disclosed |
| EP-0675118-A2 | Biphenylderivatives, process for their preparation and their use as medicaments | Eisai Co., Ltd. (JP) | 1995-10-04 | — | — | EP | disclosed |