Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 17/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 16/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 15/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8002534 | 1.00 | OPRD1 (0.39) | OPRD1OPRK1OPRM1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL8011601 | 0.87 | ESR1 (0.39) | OPRD1OPRK1 | |
| SCHEMBL7584182 | 0.86 | ESR1 (0.40) | OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL8017509 | 0.85 | G6PC1 (0.41) | OPRD1OPRK1OPRM1 | |
| Hydrochloric Acid SCHEMBL8014791 | 0.85 | CHRNB4 (0.39) | OPRD1OPRK1DRD2 | |
| Hydrochloric Acid SCHEMBL8014796 | 0.85 | CHRNB4 (0.39) | OPRD1OPRK1DRD2 | |
| SCHEMBL7588566 | 0.84 | G6PC1 (0.41) | OPRD1OPRK1OPRM1 | |
| SCHEMBL7587127 | 0.83 | CHRNB4 (0.40) | OPRD1OPRK1DRD2 | |
| SCHEMBL7587120 | 0.83 | CHRNB4 (0.40) | OPRD1OPRK1DRD2 | |
| Hydrochloric Acid SCHEMBL8011761 | 0.83 | KDM4E (0.35) | OPRD1OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0864559-B1 | Substituted amino compounds and their use as analgesic active substances | GRUENENTHAL GMBH (DE) | 2002-06-05 | — | — | EP | disclosed |
| EP-0864559-A1 | Substituted amino compounds and their use as analgesic active substances | Grünenthal GmbH (DE) | 1998-09-16 | — | — | EP | disclosed |