Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 5/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.44 |
| ▸ | GRIK3 | Q13003 | 4/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.43 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1770261 | 0.86 | MEN1 (0.46) | TSHRSMN1; SMN2L3MBTL1GAAMEN1 | |
| SCHEMBL4704534 | 0.85 | GRIA2 (0.50) | GRIA2GRIA1GRIA3GRIA4GRIK3 | |
| SCHEMBL8372771 | 0.74 | GRIA2 (0.40) | GRIA2GRIA1GRIA3GRIA4GRIK3 | |
| SCHEMBL4705859 | 0.74 | MPO (0.48) | GRIA2GRIK3GRIK2TSHRSMN1; SMN2 | |
| SCHEMBL29580191 | 0.70 | PSMB8 (0.55) | GRIA2GRIA1GRIA3GRIA4PARP1 | |
| SCHEMBL4706735 | 0.70 | PSMB8 (0.55) | GRIA2GRIA1GRIA3GRIA4PARP1 | |
| SCHEMBL6583745 | 0.70 | DAO (0.51) | SMN1; SMN2L3MBTL1MEN1CYP1A2KMT2A | |
| SCHEMBL9396483 | 0.68 | KDM4E (0.72) | GRIA2GRIA1GRIA3GRIA4TSHR | |
| SCHEMBL7349965 | 0.67 | DAO (0.66) | GRIA2GRIA1GRIA3GRIA4PARP1 | |
| SCHEMBL982104 | 0.66 | CYP1A2 (0.69) | GRIA2GRIA1GRIA3GRIA4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894831-B1 | Monoazo pigments of the quinoxaline-acetarylide type | CLARIANT GMBH (DE) | 2002-10-09 | — | — | EP | disclosed |
| US-5910577-A | YELLOW HUE, GREATER LIGHT AND WEATHER FASTNESS | CLARIANT GMBH (DE) | 1999-06-08 | — | — | US | disclosed |
| EP-0894831-A1 | Monoazo pigments of the quinoxaline-acetarylide type | Clariant GmbH (DE) | 1999-02-03 | — | — | EP | disclosed |