Isoxaflutole

Isoxaflutole

SCHEMBL7584845

CCc1cccc(C)c1N(C(=O)CCl)C(C)COC.CS(=O)(=O)c1cc(C(F)(F)F)ccc1C(=O)c1cnoc1C1CC1.O=C(O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
TTR P02766 1/20 0.43
PPOX P50336 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MRGPRX4 Q96LA9 1/20 0.31
LMNA P02545 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
PYGL P06737 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fomesafen SCHEMBL7581201 0.94 MEN1 (0.36) MEN1KMT2ATTRPPOXTDP1
Oxyfluorfen SCHEMBL7588965 0.94 MEN1 (0.35) MEN1KMT2ATTRPPOXTDP1
Isoxaflutole SCHEMBL7585871 0.94 MEN1 (0.38) MEN1KMT2ATTRPPOXTDP1
Lactofen SCHEMBL7578359 0.93 TDP1 (0.35) MEN1KMT2ATTRPPOXTDP1
Isoxaflutole SCHEMBL7577835 0.93 TDP1 (0.35) MEN1KMT2ATTRPPOXTDP1
Isoxaflutole SCHEMBL7578161 0.93 TDP1 (0.39) MEN1KMT2ATTRPPOXTDP1
Isoxaflutole SCHEMBL7582314 0.93 MEN1 (0.37) MEN1KMT2ATTRPPOXTDP1
Isoxaflutole SCHEMBL7585172 0.92 MEN1 (0.36) MEN1KMT2ATTRPPOXTDP1
Fomesafen SCHEMBL7583065 0.90 MEN1 (0.33) MEN1KMT2ATTRPPOXTDP1
Isoxaflutole SCHEMBL7582526 0.89 MEN1 (0.32) MEN1KMT2ATTRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT MEN1 4274/4885KMT2A 2099/4885TTR 1945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.