Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 9/20 | 0.50 |
| ▸ | MGAM | O43451 | 8/20 | 0.50 |
| ▸ | SI | P14410 | 3/20 | 0.46 |
| ▸ | GBA1 | P04062 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LCT | P09848 | 1/20 | 0.46 |
| ▸ | GBA2 | Q9HCG7 | 7/20 | 0.46 |
| ▸ | UGCG | Q16739 | 3/20 | 0.46 |
| ▸ | AGL | P35573 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Camiglibose SCHEMBL19510347 | 1.00 | GAA (0.50) | GAAMGAMSIGBA1TDP1 | |
| Camiglibose SCHEMBL1201508 | 1.00 | GAA (0.50) | GAAMGAMSIGBA1TDP1 | |
| Camiglibose SCHEMBL3952283 | 1.00 | GAA (0.50) | GAAMGAMSIGBA1TDP1 | |
| Camiglibose SCHEMBL2052995 | 1.00 | GAA (0.50) | GAAMGAMSIGBA1TDP1 | |
| Camiglibose SCHEMBL5186895 | 1.00 | GAA (0.50) | GAAMGAMSIGBA1TDP1 | |
| Camiglibose SCHEMBL4604473 | 1.00 | GAA (0.50) | GAAMGAMSIGBA1TDP1 | |
| Camiglibose SCHEMBL5238483 | 1.00 | GAA (0.50) | GAAMGAMSIGBA1TDP1 | |
| Camiglibose SCHEMBL614436 | 1.00 | GAA (0.50) | GAAMGAMSIGBA1TDP1 | |
| Camiglibose SCHEMBL6794338 | 1.00 | GAA (0.50) | GAAMGAMSIGBA1TDP1 | |
| Camiglibose SCHEMBL37446 | 0.99 | GAA (0.49) | GAAMGAMSIGBA1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954668-B9 | HOMO- AND HETEROCYCLIC COMPOUNDS SUITABLE AS CETP INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2012-03-21 | — | — | EP | disclosed |
| EP-1954668-B1 | HOMO- AND HETEROCYCLIC COMPOUNDS SUITABLE AS CETP INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2011-09-28 | — | — | EP | disclosed |