Camiglibose

Camiglibose

SCHEMBL614436

CO[C@H]1O[C@H](CN2C[C@H](O)[C@@H](O)[C@H](O)[C@H]2CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 9/20 0.50
▸ MGAM O43451 8/20 0.50
▸ SI P14410 3/20 0.46
▸ GBA1 P04062 2/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ LCT P09848 1/20 0.46
▸ GBA2 Q9HCG7 7/20 0.46
▸ UGCG Q16739 3/20 0.46
▸ AGL P35573 2/20 0.46
▸ MEN1 O00255 1/20 0.44
▸ LMNA P02545 1/20 0.44
▸ MAPK1 P28482 1/20 0.44
▸ KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Camiglibose SCHEMBL19510347 1.00 GAA (0.50) GAAMGAMSIGBA1TDP1
Camiglibose SCHEMBL6794338 1.00 GAA (0.50) GAAMGAMSIGBA1TDP1
Camiglibose SCHEMBL1201508 1.00 GAA (0.50) GAAMGAMSIGBA1TDP1
Camiglibose SCHEMBL4604473 1.00 GAA (0.50) GAAMGAMSIGBA1TDP1
Camiglibose SCHEMBL3952283 1.00 GAA (0.50) GAAMGAMSIGBA1TDP1
Camiglibose SCHEMBL5238483 1.00 GAA (0.50) GAAMGAMSIGBA1TDP1
Camiglibose SCHEMBL758524 1.00 GAA (0.50) GAAMGAMSIGBA1TDP1
Camiglibose SCHEMBL5186895 1.00 GAA (0.50) GAAMGAMSIGBA1TDP1
Camiglibose SCHEMBL2052995 1.00 GAA (0.50) GAAMGAMSIGBA1TDP1
Camiglibose SCHEMBL37446 0.99 GAA (0.49) GAAMGAMSIGBA1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 405 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5643874-A ANTIOBESITY AGENTS HOFFMANN-LA ROCHE INC. (US) 1997-07-01 — — US claimed
EP-4706683-A2 CHEWABLE FORMULATIONS Elanco Tiergesundheit AG (CH) 2026-03-11 — — EP disclosed
US-20260034059-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES AQUESTIVE THERAPEUTICS, INC. (US) 2026-02-05 — — US disclosed
US-12465564-B2 Oral and nasal compositions and methods of treatment AQUESTIVE THERAPEUTICS, INC. (US) 2025-11-11 — — US disclosed
US-20250339367-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES AQUESTIVE THERAPEUTICS, INC. (US) 2025-11-06 — — US disclosed
US-12403090-B2 Oral film compositions and dosage forms having precise active dissolution profiles AQUESTIVE THERAPEUTICS, INC. (US) 2025-09-02 — — US disclosed
US-20250255780-A1 SYSTEM AND METHOD FOR MAKING PERSONALIZED INDIVIDUAL UNIT DOSES CONTAINING PHARMACEUTICAL ACTIVES AQUESTIVE THERAPEUTICS, INC. (US) 2025-08-14 — — US disclosed
US-20250171497-A1 ULTRA-PURE AGONISTS OF GUANYLATE CYCLASE C, METHOD OF MAKING AND USING SAME BAUSCH HEALTH IRELAND LIMITED (IE) 2025-05-29 — — US disclosed
US-12310922-B2 System and method for making personalized individual unit doses containing pharmaceutical actives AQUESTIVE THERAPEUTICS, INC. (US) 2025-05-27 — — US disclosed
US-12290597-B2 Oral film compositions and dosage forms having precise active dissolution profiles AQUESTIVE THERAPEUTICS, INC. (US) 2025-05-06 — — US disclosed
EP-1148054-A1 Thyroid receptor ligands Pfizer Products Inc. (US) 2001-10-24 — — EP disclosed
WO-2001072692-A1 MALONAMIC ACIDS AND DERIVATIVES THEREOF AS THYROID RECEPTOR LIGANDS PFIZER PRODUCTS INC. (US) 2001-10-04 — — WO disclosed
EP-1127882-A1 Tetrazole compounds as thyroid receptor ligands Pfizer Products Inc. (US) 2001-08-29 — — EP disclosed
EP-1125579-A2 Uses of agrp-melanocortin receptor binding modulating compounds Pfizer Products Inc. (US) 2001-08-22 — — EP disclosed
EP-1099701-A1 7-[(4'-Trifluoromethyl-biphenyl-2-carbonyl)amino]-quinoline-3-carboxylic acid amides, and methods of inhibiting the secretion of apolipoprotein B Pfizer Products Inc. (US) 2001-05-16 — — EP disclosed
WO-2001024748-A1 ABSORBENT ARTICLE HAVING BARRIER SHEET AGAINST THE MIGRATION OF THE SKIN CARE COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2001-04-12 — — WO disclosed
EP-1088819-A2 6-azauracil derivatives as thyroid receptor ligands Pfizer Products Inc. (US) 2001-04-04 — — EP disclosed
WO-2000069481-A1 ABSORBENT ARTICLE WITH SKIN CARE COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2000-11-23 — — WO disclosed
WO-2000069485-A1 ABSORBENT ARTICLE WITH SKIN CARE COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2000-11-23 — — WO disclosed
US-5643874-A ANTIOBESITY AGENTS HOFFMANN-LA ROCHE INC. (US) 1997-07-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250171497-A1 ULTRA-PURE AGONISTS OF GUANYLATE CYCLASE C, METHOD OF MAKING AND USING SAME GUCY1A1, GUCY1A2, GUCY1B1 GAA 2064/4885MGAM 3560/4885SI 2899/4885
US-20260034059-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES SORD, SLC6A13, CACNA1A GAA 383/4885MGAM 713/4885SI 92/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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