Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.36 |
| ▸ | PPARD | Q03181 | 12/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 2/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7587802 | 0.93 | PPARG (0.33) | PPARGPPARDFFAR1PPARAPTPN1 | |
| SCHEMBL7589438 | 0.85 | PTPN1 (0.37) | PPARGPPARDPTPN1KDM4EMEN1 | |
| SCHEMBL7589364 | 0.85 | PPARG (0.33) | PPARGPPARDFFAR1PPARAPTPN1 | |
| SCHEMBL5854628 | 0.84 | PPARG (0.32) | PPARGPPARDFFAR1PTPN1MAOB | |
| SCHEMBL5856395 | 0.80 | PTPN1 (0.37) | PTPN1 | |
| SCHEMBL2570756 | 0.79 | MEN1 (0.47) | KDM4EMEN1MAPTKMT2A | |
| SCHEMBL5856143 | 0.79 | PPARG (0.32) | PPARGPPARDFFAR1PTPN1MAOB | |
| SCHEMBL8521150 | 0.78 | PTPN1 (0.34) | PTPN1 | |
| SCHEMBL7589620 | 0.78 | ESR1 (0.31) | — | |
| SCHEMBL7588458 | 0.77 | ESR1 (0.43) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944613-B1 | BENZOPYRAN DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |
| US-6153768-A | RECEPTOR BLOCKING ANTIESTROGENS HAVING REDUCED SIDE EFFECTS | C & C RESEARCH LABORATORIES (KR) | 2000-11-28 | — | — | US | disclosed |
| EP-0944613-A1 | NOVEL BENZOPYRAN DERIVATIVES | C & C Research Laboratories (KR) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998025916-A1 | NOVEL BENZOPYRAN DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 1998-06-18 | — | — | WO | disclosed |