Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 3/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.32 |
| ▸ | ROR1 | Q01973 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8521150 | 0.92 | PTPN1 (0.34) | PTPN1CYP19A1KCNH2TRPV1OPRD1 | |
| SCHEMBL5856395 | 0.89 | PTPN1 (0.37) | PTPN1ESR1ESR2CYP19A1KCNH2 | |
| SCHEMBL7585298 | 0.85 | PPARG (0.36) | PTPN1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL8520642 | 0.81 | PTPN1 (0.34) | PTPN1ESR1ESR2KCNH2TRPV1 | |
| SCHEMBL7587802 | 0.81 | PPARG (0.33) | PTPN1CYP19A1KCNH2TRPV1PPARG | |
| SCHEMBL7589364 | 0.80 | PPARG (0.33) | PTPN1KCNH2TRPV1PPARGPPARD | |
| SCHEMBL5856143 | 0.79 | PPARG (0.32) | PTPN1PPARGPPARD | |
| SCHEMBL5854628 | 0.79 | PPARG (0.32) | PTPN1PPARGPPARD | |
| SCHEMBL2570756 | 0.79 | MEN1 (0.47) | CYP19A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL2569699 | 0.79 | ESR1 (0.41) | ESR1ESR2CYP19A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1120162-C | Novel benzopyran derivatives | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2003-09-03 | — | — | CN | disclosed |
| EP-0944613-B1 | BENZOPYRAN DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |
| US-6153768-A | RECEPTOR BLOCKING ANTIESTROGENS HAVING REDUCED SIDE EFFECTS | C & C RESEARCH LABORATORIES (KR) | 2000-11-28 | — | — | US | disclosed |
| CN-1244863-A | Novel benzopyran derivatives | C & C RESEARCH LAB (KR) | 2000-02-16 | — | — | CN | disclosed |
| EP-0944613-A1 | NOVEL BENZOPYRAN DERIVATIVES | C & C Research Laboratories (KR) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998025916-A1 | NOVEL BENZOPYRAN DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 1998-06-18 | — | — | WO | disclosed |