Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.33 |
| ▸ | PPARD | Q03181 | 7/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | ROR1 | Q01973 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7585298 | 0.93 | PPARG (0.36) | PPARGPPARDFFAR1THRATHRB | |
| SCHEMBL7589364 | 0.92 | PPARG (0.33) | PPARGPPARDFFAR1THRATHRB | |
| SCHEMBL5854628 | 0.91 | PPARG (0.32) | PPARGPPARDFFAR1PTPN1 | |
| SCHEMBL5856395 | 0.87 | PTPN1 (0.37) | PTPN1ROR1KCNH2TRPV1CYP19A1 | |
| SCHEMBL5856143 | 0.85 | PPARG (0.32) | PPARGPPARDFFAR1PTPN1 | |
| SCHEMBL7589620 | 0.84 | ESR1 (0.31) | — | |
| SCHEMBL7588458 | 0.84 | ESR1 (0.43) | KCNH2 | |
| SCHEMBL7589438 | 0.81 | PTPN1 (0.37) | PPARGPPARDPTPN1ROR1KCNH2 | |
| SCHEMBL8520642 | 0.80 | PTPN1 (0.34) | PTPN1KCNH2TRPV1 | |
| SCHEMBL7588462 | 0.79 | ESR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1120162-C | Novel benzopyran derivatives | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2003-09-03 | — | — | CN | disclosed |
| EP-0944613-B1 | BENZOPYRAN DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |
| US-6153768-A | RECEPTOR BLOCKING ANTIESTROGENS HAVING REDUCED SIDE EFFECTS | C & C RESEARCH LABORATORIES (KR) | 2000-11-28 | — | — | US | disclosed |
| CN-1244863-A | Novel benzopyran derivatives | C & C RESEARCH LAB (KR) | 2000-02-16 | — | — | CN | disclosed |