SCHEMBL7585362

SCHEMBL7585362

Cc1ccccc1OC(Oc1ccccc1C)C(=O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.50
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44
RXRG P48443 1/20 0.44
CYP3A4 P08684 4/20 0.44
CYP1A2 P05177 3/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
HSP90AA1 P07900 1/20 0.43
ATM Q13315 1/20 0.43
TSHR P16473 3/20 0.42
MAPK1 P28482 1/20 0.42
HPGD P15428 1/20 0.42
KMT2A Q03164 2/20 0.41
MAPT P10636 1/20 0.41
MEN1 O00255 1/20 0.41
POLB P06746 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11513308 0.83 SMN1; SMN2 (0.48) SMN1; SMN2RXRARXRBRXRGCYP3A4
SCHEMBL28887350 0.81 SMN1; SMN2 (0.64) SMN1; SMN2CYP3A4CYP1A2CYP2C9CYP2C19
SCHEMBL4596240 0.79 HPGD (0.44) SMN1; SMN2RXRARXRBNPSR1L3MBTL1
SCHEMBL28508935 0.77 CYP1A2 (0.45) SMN1; SMN2RXRARXRBRXRGCYP3A4
SCHEMBL555424 0.76 KMT2A (0.46) RXRARXRBRXRGCYP3A4CYP1A2
SCHEMBL5319081 0.76 KMT2A (0.46) RXRARXRBRXRGCYP3A4CYP1A2
SCHEMBL1162259 0.76 KMT2A (0.46) RXRARXRBRXRGCYP3A4CYP1A2
SCHEMBL9423878 0.76 KMT2A (0.46) SMN1; SMN2RXRARXRBRXRGCYP3A4
SCHEMBL7585353 0.75 KMT2A (0.50) SMN1; SMN2CYP1A2CYP2C9CYP2C19NPSR1
SCHEMBL7585829 0.75 TDP1 (0.48) CYP3A4CYP1A2CYP2C9CYP2C19L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020121631-A1 Reactive monomer; reactive oligomeric resin; and aqueous polymer emulsion; provides an overprint varnish that can be applied in-line over a conventional lithographic ink. GENERAL ELECTRIC CAPITAL CORPORATION, AS AGENT 2002-09-05 US disclosed
US-5670006-A COATING A SUBSTRATE WITH A LAYER OF INTERPENETRATING NETWORK OF POLYMERIZED EPOXY MONOMERS AND ARYLATE MONOMERS, FREE RADICAL INITIATOR AND CATIONIC INITIATORS, CURING, FIXING CURED LAYER TO VIBRATING ARTICLE, REMOVING THE RELEASE LINER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-23 US disclosed
EP-0621931-B1 VIBRATION DAMPING CONSTRUCTIONS USING ACRYLATE-CONTAINING DAMPING MATERIALS MINNESOTA MINING & MFG (US) 1997-07-30 EP disclosed
EP-0476822-B1 Energy curable pressure-sensitive compositions MINNESOTA MINING & MFG (US) 1997-03-05 EP disclosed
US-5521227-A ADHESIVES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-05-28 US disclosed
EP-0526463-B1 ENERGY CURABLE CATIONICALLY AND FREE-RADICALLY POLYMERIZABLE PRESSURE-SENSITIVE COMPOSITIONS MINNESOTA MINING & MFG (US) 1996-05-22 EP disclosed
EP-0623152-B1 AN ENERGY-POLYMERIZABLE ADHESIVE, COATING, FILM AND PROCESS FOR MAKING THE SAME MINNESOTA MINING & MFG (US) 1996-01-31 EP disclosed
EP-0521112-B1 POLYMERIC MIXTURES AND PROCESS THEREFOR MINNESOTA MINING & MFG (US) 1996-01-03 EP disclosed
US-5462797-A Photoinitiator system of an organometallic complex and free radical catalyst MINNEAPOLIS MINING AND MANUFACTURING COMPANY (US) 1995-10-31 US disclosed
US-5399637-A Energy-polymerizable adhesive, coating, and film MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-03-21 US disclosed
US-5262232-A Interpenetrating polymer network of acrylate and epoxy, high temperature use MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-16 US disclosed
US-5252694-A Curable epoxy-acrylate mixture, catalyst system, peroxide, and alcohol MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-10-12 US disclosed
EP-0563057-A1 REMOVABLE ADHESIVE TAPE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-10-06 EP disclosed
US-5238744-A Tough polymeric mixtures MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-24 US disclosed
WO-1992011332-A1 REMOVABLE ADHESIVE TAPE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-07-09 WO disclosed
US-5102924-A Toughness MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-04-07 US disclosed
EP-0476822-A2 Energy curable pressure-sensitive compositions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-03-25 EP disclosed
US-4707432-A PROTECTIVE COATINGS, IMAGES CIBA-GEIGY CORPORATION (US) 1987-11-17 US disclosed
US-4119640-A ACRYLIC OR METHACRYLIC ACID, DIEPOXIDES, INKS, HEAT OR RADIATION CURABLE COATINGS UNION CARBIDE CORPORATION (US) 1978-10-10 US disclosed
US-4100046-A Radiation polymerizable cycloalkenyl derivatives of acrylated epoxidized fatty oils or fatty acids UNION CARBIDE CORPORATION (US) 1978-07-11 US disclosed