SCHEMBL4596240

SCHEMBL4596240

O=C(c1ccccc1)C(Oc1ccccc1Cl)Oc1ccccc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.44
KMT2A Q03164 6/20 0.44
MEN1 O00255 5/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
RAB9A P51151 3/20 0.44
TP53 P04637 2/20 0.44
NPC1 O15118 2/20 0.44
MITF O75030 1/20 0.44
XBP1 P17861 1/20 0.44
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
ALDH1A1 P00352 5/20 0.44
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44
GPR55 Q9Y2T6 1/20 0.44
LMNA P02545 3/20 0.43
MAPT P10636 2/20 0.43
CXCL8 P10145 1/20 0.42
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28822330 0.84 ALDH1A1 (0.46) HPGDKMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL11512407 0.84 HPGD (0.43) HPGDKMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL6082079 0.83 ALDH1A1 (0.47) HPGDKMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL10225889 0.81 ALDH1A1 (0.53) HPGDKMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL7585362 0.79 SMN1; SMN2 (0.50) HPGDKMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL9423833 0.76 ALDH1A1 (0.47) HPGDKMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL7585829 0.75 TDP1 (0.48) KMT2AMEN1TP53ALDH1A1LMNA
SCHEMBL28993106 0.75 GPR55 (0.51) HPGDKMT2AMEN1SMN1; SMN2RAB9A
Benzoin SCHEMBL11267435 0.73 LMNA (0.66) HPGDKMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL6258067 0.73 KMT2A (0.44) HPGDKMT2AMEN1SMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1877864-A2 NANOCOMPOSITE PHOTOSENSITIVE COMPOSITION AND USE THEREOF AZ Electronic Materials USA Corp. (US) 2008-01-16 EP disclosed
WO-2006109121-A2 NANOCOMPOSITE PHOTOSENSITIVE COMPOSITION AND USE THEREOF AZ ELECTRONIC MATERIALS USA CORP. (DE) 2006-10-19 WO disclosed