SCHEMBL7585353

SCHEMBL7585353

Cc1ccc(OC(Oc2ccc(C)cc2)C(=O)c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.50
MEN1 O00255 2/20 0.50
CES2 O00748 2/20 0.50
CES1 P23141 2/20 0.50
NPSR1 Q6W5P4 1/20 0.48
PPARG P37231 1/20 0.48
PPARA Q07869 1/20 0.48
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
MAPT P10636 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
LMNA P02545 2/20 0.42
CYP1A2 P05177 1/20 0.42
GAA P10253 1/20 0.42
CYP2C9 P11712 1/20 0.42
PKM P14618 1/20 0.42
CYP2C19 P33261 1/20 0.42
POLB P06746 1/20 0.42
TDP1 Q9NUW8 2/20 0.42
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7585829 0.87 TDP1 (0.48) KMT2AMEN1CES2CES1LMNA
SCHEMBL11511122 0.84 KMT2A (0.49) KMT2AMEN1CES2CES1NPSR1
SCHEMBL11512926 0.83 KMT2A (0.48) KMT2AMEN1CES2CES1NPSR1
SCHEMBL11863284 0.81 NPSR1 (0.62) KMT2AMEN1CES2CES1NPSR1
SCHEMBL2834288 0.80 KMT2A (0.45) KMT2AMEN1CES2CES1NPC1
SCHEMBL11484986 0.79 PPARG (0.50) KMT2AMEN1PPARGPPARANPC1
SCHEMBL7585362 0.75 SMN1; SMN2 (0.50) KMT2AMEN1CES2CES1NPSR1
SCHEMBL1069138 0.75 CES2 (0.54) KMT2AMEN1CES2CES1NPSR1
Benzoin SCHEMBL11863287 0.73 LMNA (0.66) KMT2AMEN1CES2CES1NPSR1
SCHEMBL16807286 0.73 NPSR1 (0.60) KMT2AMEN1CES2CES1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020121631-A1 Reactive monomer; reactive oligomeric resin; and aqueous polymer emulsion; provides an overprint varnish that can be applied in-line over a conventional lithographic ink. GENERAL ELECTRIC CAPITAL CORPORATION, AS AGENT 2002-09-05 US disclosed
US-5670006-A COATING A SUBSTRATE WITH A LAYER OF INTERPENETRATING NETWORK OF POLYMERIZED EPOXY MONOMERS AND ARYLATE MONOMERS, FREE RADICAL INITIATOR AND CATIONIC INITIATORS, CURING, FIXING CURED LAYER TO VIBRATING ARTICLE, REMOVING THE RELEASE LINER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-23 US disclosed
EP-0621931-B1 VIBRATION DAMPING CONSTRUCTIONS USING ACRYLATE-CONTAINING DAMPING MATERIALS MINNESOTA MINING & MFG (US) 1997-07-30 EP disclosed
EP-0476822-B1 Energy curable pressure-sensitive compositions MINNESOTA MINING & MFG (US) 1997-03-05 EP disclosed
US-5521227-A ADHESIVES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-05-28 US disclosed
EP-0526463-B1 ENERGY CURABLE CATIONICALLY AND FREE-RADICALLY POLYMERIZABLE PRESSURE-SENSITIVE COMPOSITIONS MINNESOTA MINING & MFG (US) 1996-05-22 EP disclosed
EP-0623152-B1 AN ENERGY-POLYMERIZABLE ADHESIVE, COATING, FILM AND PROCESS FOR MAKING THE SAME MINNESOTA MINING & MFG (US) 1996-01-31 EP disclosed
EP-0521112-B1 POLYMERIC MIXTURES AND PROCESS THEREFOR MINNESOTA MINING & MFG (US) 1996-01-03 EP disclosed
US-5462797-A Photoinitiator system of an organometallic complex and free radical catalyst MINNEAPOLIS MINING AND MANUFACTURING COMPANY (US) 1995-10-31 US disclosed
US-5399637-A Energy-polymerizable adhesive, coating, and film MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-03-21 US disclosed
EP-0563057-A1 REMOVABLE ADHESIVE TAPE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-10-06 EP disclosed
US-5238744-A Tough polymeric mixtures MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-24 US disclosed
WO-1993015333-A2 VIBRATION DAMPING CONSTRUCTIONS USING ACRYLATE-CONTAINING DAMPING MATERIALS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-05 WO disclosed
WO-1993015125-A1 AN ENERGY-POLYMERIZABLE ADHESIVE, COATING, FILM AND PROCESS FOR MAKING THE SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-05 WO disclosed
WO-1992011332-A1 REMOVABLE ADHESIVE TAPE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-07-09 WO disclosed
US-5102924-A Toughness MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-04-07 US disclosed
EP-0476822-A2 Energy curable pressure-sensitive compositions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-03-25 EP disclosed
US-4707432-A PROTECTIVE COATINGS, IMAGES CIBA-GEIGY CORPORATION (US) 1987-11-17 US disclosed
US-4119640-A ACRYLIC OR METHACRYLIC ACID, DIEPOXIDES, INKS, HEAT OR RADIATION CURABLE COATINGS UNION CARBIDE CORPORATION (US) 1978-10-10 US disclosed
US-4100046-A Radiation polymerizable cycloalkenyl derivatives of acrylated epoxidized fatty oils or fatty acids UNION CARBIDE CORPORATION (US) 1978-07-11 US disclosed