Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7583001 | 0.81 | ALDH1A1 (0.41) | TAAR1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL13944993 | 0.80 | NOS3 (0.33) | NOS3 | |
| SCHEMBL7582531 | 0.80 | NPC1 (0.39) | TAAR1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8164187 | 0.80 | MAPT (0.46) | TAAR1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL83319 | 0.80 | NPC1 (0.46) | TAAR1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL6967654 | 0.80 | TAAR1 (0.44) | TAAR1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8165766 | 0.80 | MAPT (0.46) | TAAR1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL83507 | 0.80 | NPC1 (0.47) | TAAR1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL7580846 | 0.80 | TAAR1 (0.40) | TAAR1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8415993 | 0.80 | TAAR1 (0.40) | TAAR1NPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0939755-B1 | OXAZOLINE ARTHROPODICIDES | PURDUE RESEARCH FOUNDATION (US) | 2002-10-09 | — | — | EP | claimed |
| US-6107319-A | PESTICIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-08-22 | — | — | US | claimed |
| EP-0939755-B1 | OXAZOLINE ARTHROPODICIDES | PURDUE RESEARCH FOUNDATION (US) | 2002-10-09 | — | — | EP | disclosed |
| US-6107319-A | PESTICIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0939755-A1 | OXAZOLINE ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-09-08 | — | — | EP | disclosed |
| WO-1997026249-A1 | OXAZOLINE ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-07-24 | — | — | WO | disclosed |