Serine

Serine

SCHEMBL7585491

N[C@@H](CO)C(=O)O.c1c[nH]cn1.c1cc[nH]c1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
FKBP5 Q13451 1/20 0.42
SLC7A5 Q01650 2/20 0.37
CYP3A4 P08684 1/20 0.37
SLC1A1 P43005 1/20 0.34
CYP1A2 P05177 1/20 0.33
KIF11 P52732 1/20 0.33
PTGS1 P23219 2/20 0.33
ALPI P09923 1/20 0.33
PKM P14618 1/20 0.33
XIAP P98170 1/20 0.33
GRIA1 P42261 1/20 0.32
GRIA2 P42262 1/20 0.32
GRIA3 P42263 1/20 0.32
GRIA4 P48058 1/20 0.32
HSD17B10 Q99714 1/20 0.31
ARG1 P05089 1/20 0.31
SLC7A11 Q9UPY5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Serine SCHEMBL424445 0.95 ALDH1A1 (0.46) ALDH1A1FKBP5SLC7A5CYP3A4SLC1A1
Serine SCHEMBL424443 0.95 ALDH1A1 (0.46) ALDH1A1FKBP5SLC7A5CYP3A4SLC1A1
Serine SCHEMBL29269863 0.89 ALDH1A1 (0.41) ALDH1A1FKBP5SLC7A5CYP3A4SLC1A1
Serine SCHEMBL1173209 0.84 SLC1A1 (0.45) SLC7A5SLC1A1CYP1A2KIF11PTGS1
Serine SCHEMBL28484009 0.84 SLC1A1 (0.45) SLC7A5SLC1A1CYP1A2KIF11PTGS1
Serine SCHEMBL8577869 0.83 SLC1A1 (0.38) ALDH1A1SLC7A5CYP3A4SLC1A1CYP1A2
Cysteine SCHEMBL28497338 0.80 PTGS1 (0.55) ALDH1A1FKBP5SLC7A5CYP3A4CYP1A2
Aspartic Acid SCHEMBL28155193 0.80 ALDH1A1 (0.45) ALDH1A1FKBP5SLC7A5CYP3A4SLC1A1
Imidazole SCHEMBL28128892 0.80 ALDH1A1 (0.45) ALDH1A1FKBP5SLC7A5CYP3A4SLC1A1
Serine SCHEMBL8579016 0.77 SLC1A1 (0.34) ALDH1A1SLC7A5CYP3A4SLC1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0851287-B1 Aminopolycarboxylic acid-series chelating agent, heavy metal compound thereof, photographic additive, and processing method FUJI PHOTO FILM CO LTD (JP) 2002-03-27 EP disclosed
US-5874203-A LIGHT SENSITIVE ELEMENT COMPRISING SPECIFIED COLOR-DEVELOPING AGENT CONTAINED IN HYDROPHILIC COLLOID LAYER ON BASE, AT LEAST ONE COLOR-FORMING COUPLER FUJI PHOTO FILM, CO., LTD. (JP) 1999-02-23 US disclosed
US-5851749-A Color-developing agent, silver halide photographic light-sensitive material and image-forming method FUJI PHOTO FILM CO., LTD. (JP) 1998-12-22 US disclosed
EP-0851287-A2 Aminopolycarboxylic acid-series chelating agent, heavy metal compound thereof, photographic additive, and processing method Fuji Photo Film Co., Ltd. (JP) 1998-07-01 EP disclosed
US-5756275-A IMPROVED IMAGE WHEN USING COUPLER HAVING SUBSTITUENT AT ACTIVE POSITION FUJI PHOTO FILM CO., LTD. (JP) 1998-05-26 US disclosed