Aclonifen

Aclonifen

SCHEMBL7585692

COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccsc2C(=O)O)n1.Nc1c([N+](=O)[O-])ccc(Oc2ccccc2)c1Cl.O=C(O)COc1ccc(Cl)c2cccnc12

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
TTR P02766 1/20 0.35
ALB P02768 1/20 0.35
THRB P10828 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
NPC1 O15118 2/20 0.33
RAB9A P51151 1/20 0.33
GAA P10253 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
ALOX12 P18054 1/20 0.32
CCR6 P51684 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
PKM P14618 1/20 0.32
KDM4E B2RXH2 2/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorsulfuron SCHEMBL7579708 0.92 KMT2A (0.38) KMT2AMEN1TTRALBTHRB
Aclonifen SCHEMBL7579105 0.91 KMT2A (0.37) KMT2AMEN1TTRALBTHRB
Logran SCHEMBL7591002 0.89 KMT2A (0.35) KMT2AMEN1TTRALBTHRB
Aclonifen SCHEMBL7580623 0.89 MEN1 (0.45) KMT2AMEN1TTRALBTHRB
Iodosulfuron SCHEMBL7584950 0.88 KMT2A (0.34) KMT2AMEN1TTRALBTHRB
Prosulfuron SCHEMBL7585217 0.87 KMT2A (0.35) KMT2AMEN1TTRALBTHRB
Bifenox SCHEMBL7580062 0.86 TDP1 (0.42) KMT2AMEN1TTRTDP1NPC1
Acifluorfen SCHEMBL7575451 0.85 MEN1 (0.43) KMT2AMEN1TTRTDP1L3MBTL1
Aclonifen SCHEMBL7586062 0.85 MEN1 (0.38) KMT2AMEN1TTRALBTHRB
Thifensulfuron-Methyl SCHEMBL7583365 0.85 MEN1 (0.44) KMT2AMEN1TTRALBTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT KMT2A 2099/4885MEN1 4274/4885TTR 1945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.